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Tuesday, October 20, 2020 | History

1 edition of Short-course chemotherapy for tuberculosis found in the catalog.

Short-course chemotherapy for tuberculosis

the transcript of a Witness Seminar held by the Wellcome Trust Centre for the history of medicine at UCL, London, on 3 February 2004

by Christie, D. A.

  • 321 Want to read
  • 29 Currently reading

Published by Wellcome Trust Centre for the History of Medicine at UCL in London .
Written in English

    Subjects:
  • Chemotherapy,
  • Congresses,
  • Tuberculosis

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by D.A. Christie and E.M. Tansey
    SeriesWellcome witnesses to Twentieth Century medicine -- v. 24, Witness seminar transcript, Wellcome witnesses to twentieth century medicine -- v. 24., Witness seminar transcript
    ContributionsWellcome Trust Centre for the History of Medicine at UCL
    The Physical Object
    Paginationxxi, 120 p.
    Number of Pages120
    ID Numbers
    Open LibraryOL27087444M
    ISBN 100854841040
    ISBN 109780854841042
    OCLC/WorldCa61878438

    Methods: Using an established experimental model of LTBI chemotherapy in which mice are aerosol-immunized with a recombinant bacillus Calmette-Guérin vaccine before low-dose aerosol infection with Mycobacterium tuberculosis, the efficacy of TMC alone and in combination with rifapentine was compared with currently recommended control. "Short-Course Chemotherapy for Pulmonary Tuberculosis1, 2." American Review of Respiratory Disease, (3), pp. –

    Despite 90 years of vaccination and 60 years of chemotherapy, tuberculosis (TB) remains the world’s leading cause of death from an infectious agent, exceeding human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) for the first time . "Short-Course Chemotherapy of Tuberculosis: Hail Britannia (and Friends)!." American Review of Respiratory Disease, (4_pt_1), pp. –

    The chemotherapy regimen was 2SHRZ/XHRZ. According to the duration of the chemotherapy, the patients were divided into two groups, the ultra-short-course chemotherapy group with an average duration of months, and the standard chemotherapy group with an average duration of 9 months. The same surgery was performed for patients in the two groups. One hundred and twenty children with possible diagnosis of pulmonary tuberculosis were admitted in this study for evaluating the efficacy of short course chemotherapy regimens in childhood pulmonary tuberculosis and are under follow up. In only three patients smear was positive for AFB. In 74 cases culture for AFB was done of which 18 cases (243%) were found to be positive.


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Short-course chemotherapy for tuberculosis by Christie, D. A. Download PDF EPUB FB2

Short-course chemotherapy for tuberculosis. This book is a fascinating account of the long history of tuberculosis starting in antiquity up to the latest revolutionary changes in this field. Fresh nodes, increase in size of nodes, and sinuses and abscesses occurred both during treatment and follow up.

After 36 months of follow up after treatment only 5 (3%) patients required retreatment for tuberculosis. CONCLUSION--Tuberculous lymphadenitis in children can be successfully treated with a short course chemotherapy regimen of six by: The 5-month ultra-short-course chemotherapy regimen for the initial treatment of smear-positive pulmonary tuberculosis reached a conversion rate of %, and a 3-year recurrence rate of % 9.

Therefore, we inferred that ultra-short-course chemotherapy should be feasible in the treatment of spinal by: Short-course chemotherapy for tuberculosis was suggested as a suitable topic for a Witness Seminar by Dr Owen McCarthy.

He provided many of the names of individuals to be invited, and helped decide on the topics to be discussed. We thank him for his input. We are particularly grateful to Professor. To assess the efficacy of a short course chemotherapy regimen for treating tuberculosis of the lymph nodes in children.

Open, collaborative, outpatient clinical trial. Bacteriological assessment of 60 Short-course chemotherapy for tuberculosis book tuberculosis patients on short course chemotherapy and 66 patients on retreatment was made at the time of their retrieval after various periods of.

Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis July Infection and Drug Resistance Volume 1.

Am J Med. Aug;77(2) Short-course chemotherapy for tuberculosis with mainly twice-weekly isoniazid and rifampin. Community physicians' seven-year experience with mainly outpatients. Short course chemotherapy for tuberculosis of lymph nodes: a controlled trial.

At 36 months data from patients were available for analysis, of whom 56 had received the short course regimen. Progress during chemotherapy was uneventful in 84 of the patients.

Fresh nodes appeared in 13 patients and existing nodes increased in size in. The World Health Organization (WHO) tuberculosis (TB) control strategy, directly observed treatment short-course (DOTS), consists of 5 components, including the administration of standardized short-course chemotherapy (SCC) regimens with first-line drugs (isoniazid, rifampicin, pyrazinamide, and streptomycin or ethambutol or both) under direct.

Introduction Short-course chemotherapy trials for pulmonary tuberculosis () showed that 6 months treatment with rifampicin and isoniazid, supplemented by pyra- zinamide and ethambutol or streptomycin for the first 2 months, were equally effective as 9-month therapy without pyrazinamide.

SHORT-COURSE CHEMOTHERAPY FOR TUBERCULOSIS OF THE SPINE Short-course (6 or 9 months) regimens of chemotherapy, based on daily isoniazid and rifampicin are highly effective in smear-positive pulmonary tuberculosis.4,5 A six-month regimen of daily isoniazid and rifampicin6,7 was expected to be effective in spinal tuberculosis, because of its.

Get this from a library. Short-course chemotherapy for tuberculosis: the transcript of a Witness Seminar held by the Wellcome Trust Centre for the history of medicine at UCL, London, on 3 February [D A Christie; E M Tansey; Wellcome Trust Centre for the History of Medicine at UCL.;]. Short course chemotherapy (SCC) regimens have been extensively evaluated in the treatment of pulmonary tuberculosis (TB).

To date, however, no such large-scale evaluation is available for patients who demonstrate extra-pulmonary TB [7], despite existence of a few reports on SCC in some forms of extrapulmonary TB (e.g., pleural and lymph node).

Tuberculosis Research Centre (Indian Council of Medical Research), Madras (Received original January ; revised June ) ABSTRACT A study was undertaken in North Arcot and Raichur districts in South India to find out the reasons for patients getting ‘lost’ from short course chemotherapy.

There were (40%) patients ‘lost. Tuberculosis is still the leading cause of death by a single infectious agent. Effective chemotherapy has been used and improved since the s, but strains resistant to this therapy and most. Abstract. The success of short-course chemotherapy for tuberculosis, the similarity between Mycobacterium tuberculosis and M.

kansasii and the effectiveness of rifampin against the latter organism prompted a comparison of the diseases due to these organisms to assess the feasibility of a prospective trial of short-course chemotherapy in patients with mycobacteriosis kansasii.

Although short-course, largely twice weekly chemotherapy for treatment of tuberculosis has been shown to be effective in other countries, when given under closely controlled conditions, it has not been adopted in this country where most patients are older and are treated as outpatients.

Since January,patients (mean age years) with proven pulmonary tuberculosis have been treated. Standardized short-course chemotherapy to all cases of TB under proper case-management conditions including direct observation of treatment; proper case management conditions imply technically sound and socially supportive services • Uninterrupted supply of quality-assured drugs with reliable drug procurement and distribution systems •.

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Keywords: Short course chemotherapy; Tuberculosis; Female genital organ. Introduction Treatment of pulmonary tuberculosis with short course chemotherapy (SCC) is now well established [ 6,9 ].

Apart from convenience to the patient, better compliance and less exposure to toxic drugs have been cited as points in favour of SCC.The major historical landmarks of tuberculosis (TB) therapy include: the discovery of effective medications (streptomycin and para-aminosalicylic acid) in ; the revelation of “triple therapy” (streptomycin, para-aminosalicylic acid and isoniazid) inwhich assured cure; recognition in the s that isoniazid and rifampin could reduce the duration of treatment from 18 to 9 months.Abstract.

For the treatment of smear-positive pulmonary tuberculosis, short-course chemotherapy of 6 months' duration (with the four-drug combination of isoniazid, rifampin, pyrazinamide, and either ethambutol or streptomycin given daily for a 2-month initial intensive phase followed by a 4-month daily continuation phase with isoniazid and rifampin) is as effective and as acceptable as the.